Published In
Turkish Journal of Gastroenterology
Volume 33 · Issue 1
Pages: 30-34
History
Published Online: January 15, 2022
Copyright © 2022 İbrahim Ethem Güven, Batuhan Başpınar, Roni Atalay
İbrahim Ethem Güven
Department of Gastroenterology and Hepatology, Ankara City Hospital, Ankara, Turkey
Batuhan Başpınar
Department of Gastroenterology and Hepatology, Ankara City Hospital, Ankara, Turkey
Roni Atalay
Department of Gastroenterology, Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Ankara, Turkey
Güven, İbrahim E., Başpınar, B., & Atalay, R. (2022). Relationship Between Systemic Immune-Inflammation Index and Irritable Bowel Syndrome. Turkish Journal of Gastroenterology, 33(1), 30–34. https://doi.org/10.5152/tjg.2021.21321
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Abstract
Background: Irritable bowel syndrome is accepted as a functional disorder; however, there is growing evidence in favor of the inflammatory process contributing to its pathogenesis. We aimed to evaluate the role of the systemic immune-inflammation index as a marker of
inflammation in patients with irritable bowel syndrome.
Methods: The study was conducted in the outpatient clinic of the Gastroenterology Department with patients having constipationpredominant irritable bowel syndrome diagnosis according to Rome IV criteria between March 1, 2019 and December 31, 2020. The
systemic immune-inflammation index was calculated and compared with age- and sex-matched healthy controls.
Results: The study was performed with 214 participants, 107 patients and 107 control groups. Platelet and neutrophil counts (P < .001, for
both) were higher, and lymphocyte count (P = .003) was lower in the irritable bowel syndrome group. The systemic immune-inflammation
index was higher in irritable bowel syndrome patients (P < .001). Multivariate logistic regression analyses showed the role of the systemic
immune-inflammation index as an independent predictor of the presence of IBS (odds ratio: 1.100, P < .001).
Conclusion: Systemic immune-inflammation index may be a cheap, universal, and reliable indicator of the inflammatory process in
irritable bowel syndrome patients.
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Article Info
Published In
Journal
Turkish Journal of Gastroenterology
Volume / Issue
Volume 33 · Issue 1
Pages
30-34
History
Published Online
January 15, 2022
Copyright
Copyright (c) 2022 İbrahim Ethem Güven, Batuhan Başpınar, Roni Atalay
Affiliations
İbrahim Ethem Güven
Department of Gastroenterology and Hepatology, Ankara City Hospital, Ankara, Turkey
Batuhan Başpınar
Department of Gastroenterology and Hepatology, Ankara City Hospital, Ankara, Turkey
Roni Atalay
Department of Gastroenterology, Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Ankara, Turkey
Cite this Article
Güven, İbrahim E., Başpınar, B., & Atalay, R. (2022). Relationship Between Systemic Immune-Inflammation Index and Irritable Bowel Syndrome. Turkish Journal of Gastroenterology, 33(1), 30–34. https://doi.org/10.5152/tjg.2021.21321
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