Turkish Journal of Gastroenterology
Original Article

Multidisciplinary decision making in the management of hepatocellular carcinoma: A hospital-based study

1.

Department of Tropical Medicine and Gastroenterology, Assiut University Faculty of Medicine, Assiut, Egypt

2.

Department of Radiology, Assiut University Faculty of Medicine, Assiut, Egypt

3.

Department of Oncology Surgery, Assiut University South Egypt Cancer Institute, Assiut, Egypt

4.

Department of Internal medicine, Assiut University Faculty of Medicine, Assiut, Egypt

Turk J Gastroenterol 2015; 26: 498-505
DOI: 10.5152/tjg.2015.0158
Read: 1298 Downloads: 745 Published: 25 July 2019

Abstract

Background/Aims: To evaluate the short-term outcome of the decision taken by the Hepatoma Board for the treatment of Hepatocellular carcinoma (HCC).

 

Materials and Methods: This was a prospective descriptive study involving 74 patients with HCC diagnosed by the known criteria. The decisions taken by the Hepatoma Board for the 74 patients were as follows: 1- surgical resection (7 patients), 2- local ablative therapy (LAT) (22 patients), 3- conventional transarterial chemoembolization (TACE) (24 patients), and 4- palliative supportive care (21 patients).

 

Results: The short-term mortality rate was 25.7% of the total patients. The success rate was nearly equal in LAT (68.2%) and surgery (71.4%), whereas the success rate was approximately 33.3% in TACE. There was no difference in the mean total bilirubin level before and after LAT, surgery, or TACE (p>0.05 for each). There was a significant decrease in the mean serum albumin level after TACE (p=0.000). There was a decrease in the mean alpha fetoprotein level after surgery and LAT (p=0.033) for surgery and (p=0.048) for LAT.

 

Conclusion: The management of HCC is better performed through a multidisciplinary team decision. Surgery has comparable outcome to LAT but is more invasive. According to our local experience, conventional TACE has a success rate of 33.3%. 

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EISSN 2148-5607