Published In
Turkish Journal of Gastroenterology
Volume 30 · Issue 4
Pages: 357-363
History
Published Online: July 25, 2019
Copyright © 2019 Yeliz Çağan Appak, Maşallah Baran, Mustafa Onur Öztan, Miray Karakoyun, Soysal Turhan, Cem Tuğmen, Sema Aydoğdu, Cezmi Karaca, Gökhan Köylüoğlu
Yeliz Çağan Appak
Department of Pediatric Gastroenterology Hepatology and Nutrition SBU Tepecik Training and Research Hospital İzmir Turkey
Maşallah Baran
Department of Pediatric Gastroenterology Hepatology and Nutrition İzmir Katip Çelebi University & SBU Tepecik Training and Research Hospital İzmir Turkey
Mustafa Onur Öztan
Department of Pediatric Surgery Izmir Katip Çelebi University & SBU Tepecik Training and Research Hospital İzmir Turkey
Miray Karakoyun
Department of Pediatric Gastroenterology Hepatology and Nutrition SBU Tepecik Training and Research Hospital İzmir Turkey
Soysal Turhan
Department of Cardiovascular Surgery SBU Tepecik Training and Research Hospital İzmir Turkey
Cem Tuğmen
Department of Organ Transplantation and General Surgery SBU Tepecik Training and Research Hospital İzmir Turkey
Sema Aydoğdu
Department of Pediatric Gastroenterology Hepatology and Nutrition Ege University School of Medicine İzmir Turkey
Cezmi Karaca
Department of Organ Transplantation and General Surgery SBU Tepecik Training and Research Hospital İzmir Turkey
Gökhan Köylüoğlu
Department of Pediatric Surgery Izmir Katip Çelebi University & SBU Tepecik Training and Research Hospital İzmir Turkey
Çağan Appak, Y., Baran, M., Öztan, M. O., Karakoyun, M., Turhan, S., Tuğmen, C., … Köylüoğlu, G. (2019). Assessment and outcome of pediatric intestinal pseudo-obstruction: A tertiary-care-center experience from Turkey. Turkish Journal of Gastroenterology, 30(4), 357–363. https://doi.org/10.5152/tjg.2019.18287
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Abstract
Background/Aims: Pediatric intestinal pseudo-obstruction (PIPO) is a severe disorder of gut motility. In this rare and difficult-to-manage disease, complex treatment method, such as intestinal transplantation, is sometimes needed. This study evaluated the management and follow-up results of patients with PIPO who received treatment at our center.
Materials and Methods: The cases of 13 patients with PIPO were reviewed retrospectively. Demographic data, clinical features, etiologies, pharmacological and surgical treatments, nutritional support, anthropometric findings, small bowel transplantation (SBT), and survival rates were assessed.
Results: Two of the patients were diagnosed at 1 and 5 years of age, while other patients were diagnosed during neonatal period. The etiological cause could not be identified for 5 patients. Pharmacological treatment response was observed in 38.4% of patients. Post-pyloric feeding was applied in 4 patients, but no response was observed. Gastrostomy decreased the clinical symptoms in 3 patients during the abdominal distension period. Total oral nutrition was achieved in 38.4% of the total-parenteral-nutrition (TPN)-dependent patients. It was observed that anthropometric findings improved in patients with total oral nutrition. Liver cirrhosis developed in 1 patient. Venous thrombosis developed in 4 patients. The SBT was performed on 3 patients. One of these patients has been followed up for the last 4 years.
Conclusion: Pediatric intestinal pseudo-obstruction is a rare disease that can present with a wide range of clinical symptoms. While some patients require intestinal transplantation, supportive care may be sufficient in others. For this reason, patients with PIPO should be managed individually.
Cite this article as: Çağan Appak Y, Baran M, Öztan MO, et al. Assessment and outcome of pediatric intestinal pseudo-obstruction: A tertiary-care-center experience from Turkey. Turk J Gastroenterol 2019; 30(4): 357-63.
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Article Info
Published In
Journal
Turkish Journal of Gastroenterology
Volume / Issue
Volume 30 · Issue 4
Pages
357-363
History
Published Online
July 25, 2019
Copyright
Copyright (c) 2019 Yeliz Çağan Appak, Maşallah Baran, Mustafa Onur Öztan, Miray Karakoyun, Soysal Turhan, Cem Tuğmen, Sema Aydoğdu, Cezmi Karaca, Gökhan Köylüoğlu
Affiliations
Yeliz Çağan Appak
Department of Pediatric Gastroenterology Hepatology and Nutrition SBU Tepecik Training and Research Hospital İzmir Turkey
Maşallah Baran
Department of Pediatric Gastroenterology Hepatology and Nutrition İzmir Katip Çelebi University & SBU Tepecik Training and Research Hospital İzmir Turkey
Mustafa Onur Öztan
Department of Pediatric Surgery Izmir Katip Çelebi University & SBU Tepecik Training and Research Hospital İzmir Turkey
Miray Karakoyun
Department of Pediatric Gastroenterology Hepatology and Nutrition SBU Tepecik Training and Research Hospital İzmir Turkey
Soysal Turhan
Department of Cardiovascular Surgery SBU Tepecik Training and Research Hospital İzmir Turkey
Cem Tuğmen
Department of Organ Transplantation and General Surgery SBU Tepecik Training and Research Hospital İzmir Turkey
Sema Aydoğdu
Department of Pediatric Gastroenterology Hepatology and Nutrition Ege University School of Medicine İzmir Turkey
Cezmi Karaca
Department of Organ Transplantation and General Surgery SBU Tepecik Training and Research Hospital İzmir Turkey
Gökhan Köylüoğlu
Department of Pediatric Surgery Izmir Katip Çelebi University & SBU Tepecik Training and Research Hospital İzmir Turkey
Cite this Article
Çağan Appak, Y., Baran, M., Öztan, M. O., Karakoyun, M., Turhan, S., Tuğmen, C., … Köylüoğlu, G. (2019). Assessment and outcome of pediatric intestinal pseudo-obstruction: A tertiary-care-center experience from Turkey. Turkish Journal of Gastroenterology, 30(4), 357–363. https://doi.org/10.5152/tjg.2019.18287
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