Pancreatobiliary - Original Article

Evaluation of hypertriglyceridemia-induced acute pancreatitis: A single tertiary care unit experience from Turkey

Volume 30 · Issue 3 Publish Date: July 25, 2019
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Orhan Sezgin
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Osman Özdoğan
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Serkan Yaraş
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Enver Üçbilek
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Engin Altıntaş
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Sezgin, O., Özdoğan, O., Yaraş, S., Üçbilek, E., & Altıntaş, E. (2019). Evaluation of hypertriglyceridemia-induced acute pancreatitis: A single tertiary care unit experience from Turkey. Turkish Journal of Gastroenterology, 30(3), 271–277. https://doi.org/10.5152/tjg.2018.18292
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Abstract

Background/Aims: This study aimed to determine the frequency of hypertriglyceridemia (HTG)-induced acute pancreatitis (AP) and assess different clinical and prognostic features in these patients. Materials and Methods: The patients who were hospitalized with AP due to HTG (HTG-AP) between January 2005 and December 2014 were retrospectively evaluated in the clinic. The patients with AP due to non-HTG (non-HTG-AP) were also investigated during the same period. Results: Of 635 patients with AP admitted to the clinic, 33 (5.2%) had HTG-related AP. Mean triglyceride levels were 2653 mg/dL (range: 439-13700 mg/dL). Mean Ranson score at the time of admission was 1.5, and the APACHE II score was 4.63. The mean duration of hospitalization was 4.4 days (range: 2-14 days). One of these patients died on the sixth day of hospitalization due to multiple-organ failure. Patients with a triglyceride level of >1000 mg/dL were younger, had a longer hospital stay, and had a higher recurrence rate. Compared with non-HTG-AP, HTG-AP was observed at a younger age (57.4±17.3 vs. 37.6±14.8, pConclusion: HTG-AP was observed at a younger age and was responsible for most cases of recurrent pancreatitis. The duration of hospitalization was long, and the risk of recurrence and mortality were high in patients with HTG-AP having a triglyceride level >1000 mg/dL. Cite this article as: Sezgin O, Özdoğan O, Yaraş S, Üçbilek E, Altıntaş E. Evaluation of hypertriglyceridemia-induced acute pancreatitis: A single tertiary care unit experience from Turkey. Turk J Gastroenterol 2019; 30(3): 271-7.

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Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 30 · Issue 3
Pages 271-277
History
Published Online July 25, 2019
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Affiliations
Orhan Sezgin
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Osman Özdoğan
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Serkan Yaraş
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Enver Üçbilek
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Engin Altıntaş
Department of Gastroenterology Mersin University School of Medicine Mersin Turkey
Cite this Article
Sezgin, O., Özdoğan, O., Yaraş, S., Üçbilek, E., & Altıntaş, E. (2019). Evaluation of hypertriglyceridemia-induced acute pancreatitis: A single tertiary care unit experience from Turkey. Turkish Journal of Gastroenterology, 30(3), 271–277. https://doi.org/10.5152/tjg.2018.18292
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