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The Effects and Adverse Reactions of Different Bowel Cleansers on Gut Microbiota After Colonoscopy

Volume 36 · Issue 10 Publish Date: August 11, 2025
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Jiabin Hu
Department of Geriatrics, Chinese PLA General Hospital, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Beijing, China
Xiongqun Peng ORCID
Department of Gastroenterology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Hunan, China
Shuang Cai
Medical School of Chinese PLA, Beijing, China
Jiaojiao Qiu
Department of Geriatrics, Chinese PLA General Hospital, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Beijing, China
Shuxia Wang
Department of Geriatrics, Chinese PLA General Hospital, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Beijing, China
Ping Zhu
Department of Geriatrics, Chinese PLA General Hospital, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Beijing, China
Hu, J., Peng, X., Cai, S., Qiu, J., Wang, S., & Zhu, P. (2025). The Effects and Adverse Reactions of Different Bowel Cleansers on Gut Microbiota After Colonoscopy. Turkish Journal of Gastroenterology, 36(10), 620–628. https://doi.org/10.5152/tjg.2025.25150
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Abstract

Colonoscopy is a pivotal technique for screening and diagnosing colorectal diseases, particularly colorectal polyps and cancers. Early detection of lesions enables early diagnosis and treatment, thereby improving patient prognosis. The adequacy of bowel preparation is directly related to the quality and effectiveness of colonoscopy. However, the bowel cleansing process may disrupt the balance of gut microbiota, subsequently affecting the host’s health status. Currently, there is a relative scarcity of reports on the specific impacts of different types of laxatives on gut microbiota. Therefore, this paper aims to deeply analyze and summarize the effects of various bowel preparations on gut microbiota and their potential adverse reactions following colonoscopy, providing a more comprehensive reference for the selection of bowel preparations in clinical practice.

 

Cite this article as: Hu J, Peng X, Cai S, Qiu J, Wang S, Zhu P. The effects and adverse reactions of different bowel cleansers on gut microbiota after colonoscopy. Turk J Gastroenterol. 2025;36(10):620-628.

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Article Info
Published In
Journal Turkish Journal of Gastroenterology
Volume / Issue Volume 36 · Issue 10
Pages 620-628
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Published Online August 11, 2025
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Jiabin Hu
Department of Geriatrics, Chinese PLA General Hospital, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Beijing, China
Xiongqun Peng ORCID
Department of Gastroenterology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Hunan, China
Shuang Cai
Medical School of Chinese PLA, Beijing, China
Jiaojiao Qiu
Department of Geriatrics, Chinese PLA General Hospital, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Beijing, China
Shuxia Wang
Department of Geriatrics, Chinese PLA General Hospital, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Beijing, China
Ping Zhu
Department of Geriatrics, Chinese PLA General Hospital, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Beijing, China
Cite this Article
Hu, J., Peng, X., Cai, S., Qiu, J., Wang, S., & Zhu, P. (2025). The Effects and Adverse Reactions of Different Bowel Cleansers on Gut Microbiota After Colonoscopy. Turkish Journal of Gastroenterology, 36(10), 620–628. https://doi.org/10.5152/tjg.2025.25150
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