Published In
Turkish Journal of Gastroenterology
Volume 33 · Issue 11
Pages: 955-963
History
Published Online: November 15, 2022
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright © 2022 Süleyman Dolu, Göksel Bengi, Vildan Avkan-Oğuz, Kemal Can Tertemiz, Naciye Sinem Gezer, Sema Alp Çavuş, Aylin Özgen Alpaydın, Ziya Kuruüzüm, Begüm Ergan, Can Sevinç, Gökçen Ömeroğlu Şimsek, Oğuz Kılınç, Murat Örmen, Arzu Sayıner, Işıl Somalı, Caner Çavdar, Gerçek Can, Tevfik Demir, Mesut Akarsu, Yusuf Savran, Müjde Soytürk
Süleyman Dolu
Department of Gastroenterology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Göksel Bengi
Department of Gastroenterology, Dokuz Eylül University, School of Medicine, ?zmir
Vildan Avkan-Oğuz
Department of Infectious Diseases and Clinical Microbiology, Dokuz Eylül University School of Medicine, İzmir, Turkey
Kemal Can Tertemiz
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Naciye Sinem Gezer
Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Sema Alp Çavuş
Department of Infectious Diseases and Clinical Microbiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Aylin Özgen Alpaydın
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Ziya Kuruüzüm
Department of Infectious Diseaes, Dokuz Eylül University School of Medicine, İzmir, Turkey
Begüm Ergan
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Can Sevinç
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Gökçen Ömeroğlu Şimsek
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Oğuz Kılınç
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Murat Örmen
Dokuz Eylul University School of Medicine, Departments of Hematology/Oncology, İzmir
Arzu Sayıner
Department of Medical Microbiology, Dokuz Eylül University School of Medicine, İzmir, Turkey
Işıl Somalı
Department of Medical Oncology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Caner Çavdar
Department of Nephrology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Gerçek Can
Division Rheumatology, Department of Internal Medicine, Dokuz Eylül University School of Medicine, İzmir, Turkey
Tevfik Demir
Division of Endocrinology, Dokuz Eylül University School of Medicine, İzmir, Turkey
Mesut Akarsu
Dokuz Eylül University, Faculty of Medicine, Division of Gastroenterology, İzmir, Turkey
Yusuf Savran
Department of Internal Medicine and Medical Intensive Care, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Müjde Soytürk
Departments of Gastroenterology and Pathology, Dokuz Eylül University, School of Medicine, İzmir
Dolu, S., Bengi, G., Avkan-Oğuz, V., Tertemiz, K. C., Gezer, N. S., Çavuş, S. A., … Soytürk, M. (2022). Prevalence of Gastrointestinal Symptoms and Clinical Outcomes in Hospitalized Coronavirus Disease 2019 Patients: A Single-Center Study from Turkey. Turkish Journal of Gastroenterology, 33(11), 955–963. https://doi.org/10.5152/tjg.2022.21484
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Abstract
Background: In patients with coronavirus disease 2019, the gastrointestinal symptoms have been reported increasingly in addition to the respiratory system symptoms. The studies show that the prevalence of gastrointestinal system symptoms and how the gastrointestinal system contributes to the severity and prognosis of the disease is still not clear. This study aims to find the prevalence of gastrointestinal symptoms and the correlation between the gastrointestinal symptoms and the clinical results in hospitalized patients diagnosed with coronavirus disease 2019. Methods: This study retrospectively analyzes patients diagnosed with coronavirus disease 2019 and hospitalized in the pandemic unit between March 2020 and August 2020 and compares their demographic and clinical characteristics, laboratory and radiologic findings, coronavirus disease 2019 treatments received, the clinical course of the disease, and the gastrointestinal symptoms. Results: In our study, we included 322 patients diagnosed with coronavirus disease 2019 and hospitalized; 39 patients (12.1%) were admitted to the hospital with at least one gastrointestinal symptom (nausea and vomiting, diarrhea, abdominal pain, and the loss of taste). Nausea and vomiting are the most common gastrointestinal symptoms with a prevalence of 7.1%, followed by diarrhea with 2.8%, the loss of taste with 2.2%, and abdominal pain with 1.5%. The mean age and D-dimer levels of the patients showing gastrointestinal symptoms were lower than those who did not have any gastrointestinal symptoms. We did not find a significant correlation between the presence of the gastrointestinal symptoms and the severity of the disease, treatment received, risk of acute respiratory distress syndrome and septic shock, admission to the intensive care unit, the need for mechanical ventilation, the mortality rate or the length of hospitalization in the medical floor or the intensive care unit. Conclusion: In this study, we observed that 12.1% of coronavirus disease 2019 patients apply to the hospital due to gastrointestinal symptoms. Furthermore, the gastrointestinal symptoms do not seem to affect the severity and the course of the disease, it is important to identify coronavirus disease 2019 patients showing unusual symptoms such as the gastrointestinal symptoms at an early stage to protect healthcare professionals from infection risk. Cite this article as: Dolu S, Bengi G, Avkan-Oğuz V, et al. Prevalence of gastrointestinal symptoms and clinical outcomes in hospitalized coronavirus disease 2019 patients: A single-center study from Turkey. Turk J Gastroenterol. 2022;33(11):955-963.
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Article Info
Published In
Journal
Turkish Journal of Gastroenterology
Volume / Issue
Volume 33 · Issue 11
Pages
955-963
History
Published Online
November 15, 2022
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright
Copyright (c) 2022 Süleyman Dolu, Göksel Bengi, Vildan Avkan-Oğuz, Kemal Can Tertemiz, Naciye Sinem Gezer, Sema Alp Çavuş, Aylin Özgen Alpaydın, Ziya Kuruüzüm, Begüm Ergan, Can Sevinç, Gökçen Ömeroğlu Şimsek, Oğuz Kılınç, Murat Örmen, Arzu Sayıner, Işıl Somalı, Caner Çavdar, Gerçek Can, Tevfik Demir, Mesut Akarsu, Yusuf Savran, Müjde Soytürk
Affiliations
Süleyman Dolu
Department of Gastroenterology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Göksel Bengi
Department of Gastroenterology, Dokuz Eylül University, School of Medicine, ?zmir
Vildan Avkan-Oğuz
Department of Infectious Diseases and Clinical Microbiology, Dokuz Eylül University School of Medicine, İzmir, Turkey
Kemal Can Tertemiz
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Naciye Sinem Gezer
Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Sema Alp Çavuş
Department of Infectious Diseases and Clinical Microbiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Aylin Özgen Alpaydın
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Ziya Kuruüzüm
Department of Infectious Diseaes, Dokuz Eylül University School of Medicine, İzmir, Turkey
Begüm Ergan
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Can Sevinç
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Gökçen Ömeroğlu Şimsek
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Oğuz Kılınç
Department of Pulmonary Diseases, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Murat Örmen
Dokuz Eylul University School of Medicine, Departments of Hematology/Oncology, İzmir
Arzu Sayıner
Department of Medical Microbiology, Dokuz Eylül University School of Medicine, İzmir, Turkey
Işıl Somalı
Department of Medical Oncology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Caner Çavdar
Department of Nephrology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Gerçek Can
Division Rheumatology, Department of Internal Medicine, Dokuz Eylül University School of Medicine, İzmir, Turkey
Tevfik Demir
Division of Endocrinology, Dokuz Eylül University School of Medicine, İzmir, Turkey
Mesut Akarsu
Dokuz Eylül University, Faculty of Medicine, Division of Gastroenterology, İzmir, Turkey
Yusuf Savran
Department of Internal Medicine and Medical Intensive Care, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
Müjde Soytürk
Departments of Gastroenterology and Pathology, Dokuz Eylül University, School of Medicine, İzmir
Cite this Article
Dolu, S., Bengi, G., Avkan-Oğuz, V., Tertemiz, K. C., Gezer, N. S., Çavuş, S. A., … Soytürk, M. (2022). Prevalence of Gastrointestinal Symptoms and Clinical Outcomes in Hospitalized Coronavirus Disease 2019 Patients: A Single-Center Study from Turkey. Turkish Journal of Gastroenterology, 33(11), 955–963. https://doi.org/10.5152/tjg.2022.21484
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