ISSN 1300-4948 | E-ISSN 2148-5607
Review
Which diseases are risk factors for developing gastroesophageal reflux disease?
1 Department of Gastroenterology, İstanbul University İstanbul School of Medicine, İstanbul, Turkey  
2 Clinic of Gastroenterology, Tekirdağ State Hospital, Tekirdağ, Turkey  
Turk J Gastroenterol 2017; 28: 44-47
DOI: 10.5152/tjg.2017.12
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Key Words: Gastroesophageal reflux disease, pathogenesis of GERD, sarcoidosis, amyloidosis, hypothyroidism, rheumatoid arthritis, mixed connective tissue disease, Sjögren's syndrome, systemic sclerosis, diabetes mellitus, cholecystectomy, sleeve gastrectomy, sleep apnea syndrome, chronic obstructive lung disease, asthma
Abstract

Although the pathophysiology of gastroesophageal reflux disease (GERD) remains unclear, it is accepted as a multifactorial disease. It is thought that some of the interventions that might cause alterations in the normal gastrointestinal tract anatomy and diseases that affect the lower esophageal sphincter, esophageal clearance, and stomach motility (gastric emptying) might lay a foundation for GERD development. Moreover, it is common knowledge that GERD might cause various extraesophageal symptoms and complications. A possible connection between GERD and sarcoidosis, amyloidosis, hypothyroidism, rheumatoid arthritis, mixed connective tissue disorders, Sjögren’s syndrome, systemic sclerosis, diabetes mellitus, cholecystectomy, sleeve gastrectomy, sleep apnea syndrome, chronic obstructive pulmonary disease, and asthma were summarized in this literature review. 

 

 

Cite this article as: Akyüz F, Mutluay Soyer Ö. Which diseases are risk factors for developing gastroesophageal reflux disease? Turk J Gastroenterol 2017;28(Suppl 1); S44-S47

 

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