ISSN 1300-4948 | E-ISSN 2148-5607
Review
Medical treatment of gastroesophageal reflux disease
1 Division of Gastroenterology, Ege University School of Medicine, İzmir, Turkey  
2 Clinic of Gastroenterology, Türkiye Yüksek İhtisas Training and Research Hospital, Ankara, Turkey  
Turk J Gastroenterol 2017; 28: 48-52
DOI: 10.5152/tjg.2017.13
This article was viewed 0 times, downloaded 1 times

Key Words: Treatment, reflux, remission, on-demand, cessation
Abstract

Proton pump inhibitors (PPIs) are the most effective agents in the first-line and maintenance treatment of gastroesophageal reflux disease. As the grade of esophagitis increases, an increase is also observed in the level of endoscopic response to PPIs. In the first-line therapy of patients with severe esophagitis (Los Angeles (LA) Grade C-D), administration of a standard dose of PPIs bid has been reported to be more beneficial than PPIs qd. While any intermittant and low dose-continuous treatment can be chosen for the maintenance therapy of patients with non-erosive reflux disease or mild esophagitis (LA Grade A-B), continuous use of a standard dose of PPIs is preferred in the maintenance therapy of patients with severe esophagitis (LA Grade C-D). In patients who use PPIs for a long time, the drug must be stopped by gradually decreasing the dose.

 

 

Cite this article as: Bor S, Kalkan İH. Medical treatment of gastroesophageal reflux disease. Turk J Gastroenterol 2017;28(Suppl 1); S48-S52

 

Full Text Turkish

Key Words
Authors
All
Reviewer's Corner
Author’s Corner
Survey
AVES | Copyright © 2017 Turkish Society of Gastroenterology | Latest Update: 30.11.2017